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FRONTLINE Plus for Dogs Flea and Tick Treatment (Large Dog, 45-88 lbs.) 6 Doses (Purple Box)
Purchase options and add-ons
Brand | Frontline |
Item Form | Topical |
Scent | Unscented |
Age Range (Description) | Senior |
Item Weight | 0.2 Ounces |
Active Ingredients | fipronil and (S)-methoprene |
Item Volume | 1 Milliliters |
Target Species | Dog |
Allergen Information | Abalone Free |
Dog Breed Size | Large |
About this item
- Keep your dog protected from fleas & ticks all month long with FRONTLINE Plus for Dogs a fast-acting, waterproof flea & tick topical that's proven to kill fleas, flea eggs, flea larvae, chewing lice, and ticks that can transmit Lyme disease.
- Break the flea life cycle with FRONTLINE Plus. Specially formulated with fipronil and (S)-methoprene to kill existing adult fleas, flea eggs and flea larvae to guard against further infestations for flea control.
- Trusted by pet owners for over 20 years, FRONTLINE Plus for Dogs can be used on puppies as young as eight weeks old, weighing 5 pounds or more, and is easy to apply with one monthly dose providing protection from fleas & ticks for a full 30 days.
- FRONTLINE Plus also comes in a formula designed for cats and kittens eight weeks of age and older, 1.5lbs. and over so you can protect the dogs or cats in your house from fleas and ticks with FRONTLINE Brand Products.
- Treat all dogs or cats in your household monthly to effectively control fleas and ticks and prevent the establishment of new flea infestations.
- Subscribe & save today to make it easier to keep your dogs or cats protected year-round and make sure you never run out of FRONTLINE Plus.
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This Item FRONTLINE Plus for Dogs Flea and Tick Treatment (Large Dog, 45-88 lbs.) 6 Doses (Purple Box) | Recommendations | dummy | dummy | dummy | dummy | |
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Price | $78.98$78.98 | $94.99$94.99 | -13% $54.99$54.99 List: $62.99 | $79.98$79.98 | -12% $79.98$79.98 List: $91.18 | -26% $59.98$59.98 List: $81.58 |
Delivery | Get it as soon as Tuesday, Mar 26 | Get it as soon as Tuesday, Mar 26 | Get it as soon as Tuesday, Mar 26 | Get it as soon as Tuesday, Mar 26 | Get it as soon as Tuesday, Mar 26 | Get it as soon as Tuesday, Mar 26 |
Customer Ratings | ||||||
Easy to use | 4.0 | 4.4 | 4.4 | 4.2 | 4.2 | 5.0 |
Value for money | 3.1 | 3.8 | 3.8 | 3.4 | 3.5 | 3.4 |
Comfort | 3.0 | 4.6 | 4.6 | 3.6 | 3.5 | 4.1 |
Scent | 4.0 | 4.4 | 4.4 | 3.7 | — | 3.9 |
Flavor | — | 2.6 | 2.6 | — | 2.8 | — |
Sold By | Amazon.com | Amazon.com | Amazon.com | Amazon.com | Amazon.com | Amazon.com |
target audience | Dog, Dog, Dog, Dog, Dog | Adult | Adult | Dog | Dog | — |
age range | Senior | All Life Stages | All Life Stages | 7 weeks and older | 7 weeks and older | 7 weeks and older |
scent | Unscented | No Scent | No Scent | — | Unscented | Unscented |
form | Topical | Stick | Stick | Topical | Topical | Collar |
volume | 1 milliliters | 16.08 milliliters | 8.04 milliliters | 1 quarts | 24 milliliters | — |
active ingredients | fipronil and (S)-methoprene | Fipronil, (S)-methoprene, Pyriproxyfen | Fipronil, (S)-methoprene, Pyriproxyfen | Imidacloprid, Permethrin, Pyriproxyfen | Imidacloprid, Permethrin, Pyriproxyfen | Imidacloprid, Flumethrin |
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From the brand
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THE #1 NAME IN FLEA & TICK PROTECTION*
FRONTLINE Brand Products are effective topical solutions designed to help protect dogs and cats from fleas and ticks. FRONTLINE Plus and FRONTLINE Gold have formulas for dogs or cats. FRONTLINE Shield, with added mosquito repellency, is for dogs only.
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What is FRONTLINE?
FRONTLINE Brand Products are effective, easy-to-apply topical flea & tick preventives. FRONTLINE Plus and FRONTLINE Gold have formulas for dogs or cats. FRONTLINE Shield is for dogs only. All FRONTLINE Brand Products feature waterproof formulas that last a full 30 days.
Why should I protect my dog or cat from fleas & ticks?
Fleas & ticks are a year-round threat. FRONTLINE Brand Products help protect dogs or cats from these pests and monthly use can help prevent infestations.
From the manufacturer
How to Apply FRONTLINE Plus for Dogs
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Read full instructions on packaging before use. Shown here: Size Large 45-88 lbs. |
Use scissors to separate one blister. Hold applicator upright with foil side toward you and snap applicator tip off. |
Part dog’s hair between shoulder blades until skin is visible. |
Place applicator tip directly against exposed skin and apply entire contents directly to the skin. Do not apply on top of hair. |
FRONTLINE Plus for Small Dogs | FRONTLINE Plus for Medium Dogs | FRONTLINE Plus for Large Dogs | FRONTLINE Plus for X-Large Dogs | FRONTLINE Plus for Cats | |
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Customer Reviews |
4.4 out of 5 stars
43,518
|
4.4 out of 5 stars
20,938
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4.5 out of 5 stars
13,621
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4.6 out of 5 stars
3,618
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4.4 out of 5 stars
43,293
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Recommended pet size | 5 to 22 pounds | 23 to 44 pounds | 45 to 88 pounds | 89 to 132 pounds | Cats and kittens over 1.5 pounds |
Kills adult fleas, flea eggs, and flea larvae | ✓ | ✓ | ✓ | ✓ | ✓ |
Kills ticks and chewing lice | ✓ | ✓ | ✓ | ✓ | ✓ |
Minimum age of pet for use | Dogs and puppies 8 weeks and older | Dogs and puppies 8 weeks and older | Dogs and puppies 8 weeks and older | Dogs and puppies 8 weeks and older | Cats and kittens 8 weeks and older |
Available sizes | 3, 6 and 8-Dose | 3, 6 and 8-Dose | 3, 6 and 8-Dose | 3, 6 and 8-Dose | 3, 6 and 8-Dose |
Do not use on cats | Do not use on cats | Do not use on cats | Do not use on cats | For use on cats only |
Product details
- Is Discontinued By Manufacturer : No
- Product Dimensions : 5.75 x 1 x 4.5 inches; 0.2 ounces
- Item model number : 72219
- Department : Pet Supplies
- Date First Available : October 2, 2001
- Manufacturer : Boehringer Ingelheim Animal Health
- ASIN : B0002J1FOO
- Country of Origin : France
- Best Sellers Rank: #1,516 in Pet Supplies (See Top 100 in Pet Supplies)
- #13 in Dog Flea Drops
- Customer Reviews:
Product Description
Product Description
Keep your dog protected with the #1 name in flea & tick protection*, FRONTLINE®. FRONTLINE Plus for Dogs is a fast-acting, long-lasting waterproof flea & tick topical that's proven to kill fleas, flea eggs, flea larvae, chewing lice, and ticks that can transmit Lyme disease. Break the flea life cycle — FRONTLINE Plus for Dogs is specially formulated with fipronil and (S)-methoprene to kill existing adult fleas, flea eggs and flea larvae to guard against further infestations for flea control. Trusted by pet owners for over 20 years**— FRONTLINE Plus for Dogs can be used on puppies as young as eight weeks old, weighing 5 pounds or more, and is easy to apply. Applied to a single point on your pet, the flea and tick control treatment covers your dog's entire body and deposits in the sebaceous glands. These glands act as a reservoir, continuously replenishing the treatment onto your pet, working even if your dog gets wet. Just one dose of FRONTLINE Plus each month protects against fleas & ticks for a full 30 days. FRONTLINE Plus also comes in a formula designed for cats and kittens eight weeks of age and older, 1.5lbs. and over so you can protect the dogs or cats in your house from fleas and ticks with FRONTLINE Brand Products. Appropriately treat all pets in your household monthly to effectively control fleas and ticks and prevent the establishment of new flea infestations. Subscribe and save today to make it easier to keep your dogs or cats protected year-round and make sure you never run out of FRONTLINE Plus. Be sure to visit our brand store and follow us to stay up to date on new FRONTLINE products, features, tips and more. References: *Data on file at Boehringer Ingelheim. **Data showing 20 years of trust in killing fleas and ticks is on file at Boehringer Ingelheim.
Brand Story
By Frontline Plus
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Videos
Videos for this product
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Honest Review of Frontline Plus for Dogs
Reviews with Carissa
Videos for this product
0:30
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How To Apply Frontline Plus For Dogs
Boehringer Ingelheim Animal Health
Important information
Safety Information
KEEP OUT OF REACH OF CHILDREN. WARNING: PRECAUTIONARY STATEMENTS - HAZARDS TO HUMANS: WARNING. Causes substantial but temporary eye injury. Do not get in eyes or on clothing. Avoid Contact with skin. Harmful if swallowed. Wash thoroughly with soap and water after handling and before eating, drinking, chewing gum, using tobacco or using the toilet. Remove and wash clothing that may have come in contact with the product before reuse. HAZARDS TO DOMESTIC ANIMALS: For external use on dogs ONLY. Do not use on animals other than dogs. Do not use on dogs under 9 weeks of age or weighing less than 5 lbs. Individual sensitivities may occur after using ANY pesticide product. Dogs may experience some temporary irritation at the site of product application. If signs of sensitivity occur, bathe your dog with mild soap or shampoo and rinse with large amounts of water. If signs of sensitivity occur and persist, contact a veterinarian immediately. If your dog has an unusual reaction to the initial application, consult a veterinarian before repeating application. Certain medications can interact with pesticides. Consult a veterinarian before using on medicated, debilitated, aged, pregnant or nursing dogs, or dogs known to be sensitive to pesticide products. Consult a veterinarian for guidance on use against Sarcoptes mites. This product is not a substitute for a prescribed heartworm preventative.nCall 1-888-637-4251, for assistance. PHYSICAL OR CHEMICAL HAZARDS: Do not allow this product to come in contact with an oxidizing agent, as a hazardous chemical reaction may occur Harmful if swallowed. Causes substantial but temporary eye injury. Do not get in eyes or on clothing. Avoid contact with skin. Wear (specify appropriate protective eyewear such as goggles, face shield, or safety glasses). Wash thoroughly with soap and water after handling and before eating, drinking, chewing gum, using tobacco or using the toilet. Remove and wash contaminated clothing before reuse.
Ingredients
Fipronil (9.8%)|(S)-Methoprene (8.8%)
Directions
Directions for Use Step 1. To REMOVE Applicator: 1. Use scissors to separate one blister; 2. Use scissors to cut along dotted line; 3. Peel down foil to remove the applicator. Step 2. OPEN Applicator. Hold upright with foil side toward you and snap applicator tip. Step 3. APPLY FRONTLINE Plus. Part the dog’s hair between the shoulder blades. Place the applicator tip just above the skin and squeeze. Apply entire contents of the applicator in a single spot directly onto the dog’s skin. Do not apply on top of the hair coat. Avoid contact with treated area until dry. Do not allow your dog to ingest the product. Do not apply to dogs weighing less than 45 lbs. or younger than 8 weeks of age. Do not use more than one application per dog per month. Frequency Use monthly to control fleas and ticks. Do not reapply FRONTLINE Plus for 30 days.
Legal Disclaimer
Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings, and directions before using or consuming a product.
Customer reviews
Customer Reviews, including Product Star Ratings help customers to learn more about the product and decide whether it is the right product for them.
To calculate the overall star rating and percentage breakdown by star, we don’t use a simple average. Instead, our system considers things like how recent a review is and if the reviewer bought the item on Amazon. It also analyzed reviews to verify trustworthiness.
Learn more how customers reviews work on AmazonCustomers say
Customers like the side effects and value of the pet supplies. For example, they mention it helps keep pets healthy and is good value for money. Some are happy with ease of use, and quality. That said, opinions are mixed on fleas, scratching, performance, and ticks.
AI-generated from the text of customer reviews
Customers like the value of the pet supplies. They say it's worth the extra money, works well, and is cheap.
"Compared to a lot of dog flea and tick medicine, this is a reasonable price. Always ships on time as well...." Read more
"...exceed 750PPM companies continue to ignore the guidline because it's cheap and effective, and sadly it's our dogs that pay the price...." Read more
"...It's easy to apply, but as it only lasts a month, it can get expensive. But then again, it's worth it to avoid another fleafestation." Read more
"Good value" Read more
Customers are satisfied with the quality of the pet supplies. They mention that it is a great product, easy to apply, and genuine. Some say that the product stands up to swimming and that the fleas begin to die within the first 30 minutes.
"...The day after that, we had 2 different dogs. They have been so peaceful and restful since we applied this. I have not seen them scratch one time...." Read more
"...Their coats are shiny, they're not scratching every two seconds, and they've even started to learn new tricks...." Read more
"...My shipment did come directly from Amazon so I am happy to know it is genuine and safe to use on my 80# dog...." Read more
"The quality is there and it seems safe to use on him" Read more
Customers find the pet supplies easy to use. They mention it's easy to apply once a month, and has never experienced any side-effects. The application process is as smooth as butter, and it comes right to their door, making it more convenient.
"...The application process was as smooth as butter (or should I say, peanut butter – my doggos' favorite treat)...." Read more
"...Also, a problem here. So easy to apply and I don't detect a scent at all." Read more
"This products works well on my three huskies. Easy to apply. The dog don’t mind me applying it to there back." Read more
"...It's easy to apply, but as it only lasts a month, it can get expensive. But then again, it's worth it to avoid another fleafestation." Read more
Customers like the side effects of the pet supplies. They say it has the least effect on their animals, helps keep them healthy, and is great for their immune system. Some customers also mention that their dogs appear happier and are free of fleas, ticks, and lice.
"...It dries pretty quickly. This is perfect for my dogs that like to roll around in the grass and could bring anything in the house...." Read more
"...works better for ticks than Advantix/Advantage and is a better choice for cat owners (we used to have a cat, too)...." Read more
"Very easy to administer. Keeps all the crazy bugs away." Read more
"...is essentially a poison to ticks and fleas, it also has a short term effect on the dog (usually mild diarrhea)...." Read more
Customers are mixed about the performance of the pet supplies. Some mention that it works just as good as the vet flea medicine, is effective, and cheap. However, others say that it doesn't seem effective at all anymore, works for about a week then stops working, and is useless.
"...companies continue to ignore the guidline because it's cheap and effective, and sadly it's our dogs that pay the price...." Read more
"...This makes me suspect that it is not quite as effective as it would be on a dog at 45 lbs...." Read more
"This products works well on my three huskies. Easy to apply. The dog don’t mind me applying it to there back." Read more
"...However, two of my dogs (littermates) had a weird reaction to it...." Read more
Customers are mixed about the fleas. Some mention that the product does keep them from getting flea, while others say that it didn't keep flea off.
"...Always ships on time as well. My dog has had no issues with fleas or ticks since using this brand." Read more
"Must be watered down because it didnt keep fleas off but for about a week and 1/2. I wont buy Frontline product anymore." Read more
"This is hands-down the best flea and tick preventative made...." Read more
"...And while I wonder how it affects a dog's health, it does keep them from getting fleas...." Read more
Customers are mixed about the ticks. Some mention that it eliminates a lot of ticks, while others say that it doesn't seem to repel them.
"...This pretty much removed all the ticks and most of the fleas. With regular use we hardly ever see a flea...." Read more
"This worked great on my dogs! I did not find any ticks on them a couple of days after applying. Feel sure it is the real deal!..." Read more
"...This year towards the end of summer we started noticing ticks on the dogs...." Read more
"...No fleas, no ticks, no problems." Read more
Customers are mixed about the scratching with some customers saying it doesn't cause irritation or rashes, and it stops scratching after a day of treating their pet. However, other customers say it makes their pets itchy and makes them scratch and bite like crazy.
"...It's pretty nasty stuff, you're supposed to avoid getting in on your skin and wash your hands immediately afterwards...." Read more
"...Their coats are shiny, they're not scratching every two seconds, and they've even started to learn new tricks...." Read more
"...developed a horrible smell as it reacted to their skin, and they began itching and scratching furiously at the application site...." Read more
"...These drops work well, without making her itchy." Read more
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I made sure
it said "Ships from and sold by Amazon.com" ✓
Frontline inserts were in box ✓
the applicators had spaces between them ✓
the lot # on the applicator matched the lot number on the box ✓
the applicators each said Merial ✓
each applicator had instructions on how to open✓
The box I got did not look like the box on Amazon site, which worried me as it was the first thing I noticed. But I looked on Frontline's website and the 45 - 88 lb box they show looks like mine. The one on Amazon is an older model box, apparently.
Here is the real proof and the reason for my 5 stars.I have two labs. They are outdoor dogs(except for thunderstorms, snow, cold, etc) and they have never really had a problem with fleas before. When I take them to the groomers and ask if they had fleas, they usually say "one or two" but this year they were suffering. We noticed it and I immediately went to my trusty Amazon to see if it was sold, and I found all the concerns. I trust Amazon, so I ordered. As I am a prime member I knew I would get 2 days shipping, The next day I felt like a horrible dog owner. They were both whining and I could see fleas. They were miserable. The next day the package came in and I immediately did my check offs to prove it was legit. When it passed, we applied to our dogs. That night it was thundering so the babies came in. They sleep on their own indoor blankets. They were still itching but the next morning, we saw dead fleas all over the blanket. The day after that, we had 2 different dogs. They have been so peaceful and restful since we applied this. I have not seen them scratch one time. And we have not been able to find a flea or tick on them. I bought the 6 pack which will last my 2 dogs 3 months and I will apply again. If you are debating on whether to purchase or not, go ahead. I have the photos to prove it is legit, and the happy dogs as more proof If I could give it 10 stars I would. If someone had a way to convince me this was not authentic, I would still buy it because my dogs are proof enough to me that it works. But I believe it to be 100% legitimate.
Reviewed in the United States on June 9, 2015
I made sure
it said "Ships from and sold by Amazon.com" ✓
Frontline inserts were in box ✓
the applicators had spaces between them ✓
the lot # on the applicator matched the lot number on the box ✓
the applicators each said Merial ✓
each applicator had instructions on how to open✓
The box I got did not look like the box on Amazon site, which worried me as it was the first thing I noticed. But I looked on Frontline's website and the 45 - 88 lb box they show looks like mine. The one on Amazon is an older model box, apparently.
Here is the real proof and the reason for my 5 stars.I have two labs. They are outdoor dogs(except for thunderstorms, snow, cold, etc) and they have never really had a problem with fleas before. When I take them to the groomers and ask if they had fleas, they usually say "one or two" but this year they were suffering. We noticed it and I immediately went to my trusty Amazon to see if it was sold, and I found all the concerns. I trust Amazon, so I ordered. As I am a prime member I knew I would get 2 days shipping, The next day I felt like a horrible dog owner. They were both whining and I could see fleas. They were miserable. The next day the package came in and I immediately did my check offs to prove it was legit. When it passed, we applied to our dogs. That night it was thundering so the babies came in. They sleep on their own indoor blankets. They were still itching but the next morning, we saw dead fleas all over the blanket. The day after that, we had 2 different dogs. They have been so peaceful and restful since we applied this. I have not seen them scratch one time. And we have not been able to find a flea or tick on them. I bought the 6 pack which will last my 2 dogs 3 months and I will apply again. If you are debating on whether to purchase or not, go ahead. I have the photos to prove it is legit, and the happy dogs as more proof If I could give it 10 stars I would. If someone had a way to convince me this was not authentic, I would still buy it because my dogs are proof enough to me that it works. But I believe it to be 100% legitimate.
So I decided to go back to Frontline. When those doses ran out, I went to get some more and was shocked to find out that my vet no longer carried it. I don't know if he based this on personal experience, customer feedback, or what was in the media, but he stated that it was largely ineffective and they wouldn't be restocking. Can't use the oral flea meds b/c they caused horrible green bile vomiting in my dogs, so I crossed my fingers that an online source would have Frontline. Compared Amazon's prices to Petmeds and Amazon beat them soundly. Dosed up my dogs and the scratching stopped (they had picked up a few fleas as I was a bit lazy in getting some more Frontline and then had to have it mail delivered). I'd seen another review that listed all the dangers of counterfeit Frontline, but I compared my order from Posh Poodle Dog Grooming, and everything checks out as genuine...especially the fact that we no longer have any fleas. Very happy with my purchase, and for the fact that it still works well at killing and preventing flea infestation.
On that note, it's my hope the following information has some value for you.
Frontline was first put into clinical trials in 1985 shortly after the discovery of it's active ingredient Fipronil. To it's credit Frontline has maintained the safest albeit not the most effective treatment for fleas and ticks. However, the more effective products pose a significantly greater risk to your dog.
It's a slippery slope, but in evaluating what's best for your dog by providing the highest level protection with the lowest risk Frontline and FrontLine Plus are in my opinion your best bet.
Most tick and flea products contain Permethrin which may also be listed as Lyclear or Nix as the active ingredient. Permethrin is a lethal neurotoxin that flows through the dogs circulatory system and flushes into every major organ - including the brain where it can do dire damage. Thousands of dogs die every year from Permethrin. Although the FDA has mandated a minimal use not to exceed 750PPM companies continue to ignore the guidline because it's cheap and effective, and sadly it's our dogs that pay the price.
What makes Permethrin so dangerous is that it can't distinguish between insects and mammals which of course includes human beings. It's been known to be lethal to cats since the 1970's. In fact it's so deadly to cats that even a slight transfer from dog to cat can result in seizures, brain damage and death. Permethrin is volatile as well - meaning it's airborne properties pose a threat to all who breath it in - humans included.
Frontline on the other hand uses Fipronil. Fipronil is an insecticide.
Like any chemical of this nature it can be lethal at too high of a dose. However studies including those from the Department of Environmental Conservation have determined time and time again that as long as the amount of Fipronil is at the correct dose for the weight and size of your dog toxicity is far easier to avoid and the product much safer for your dog. Unlike Premethrin, Fipronil is absorbed into the hair follicles and oil glands only. It is not absorbed into the dogs system nor is it volatile so you and your beloved pets and children can breath easy. The second active ingredient in FrontLine Plus is Methoprene which is a long existing and time proven IGR (insect growth regulator) it's distributed exactly like Fipronil but only acts on flea and tick eggs and Larvae - this is important because it kills these vermin at the start of a new life cycle. What is more, the diseases that ticks carry now are infinitely more serious than the dreaded Lime disease - which for decades was the only concern.
Competitors to Frontline (and some Vets selling other products) claim that fleas and ticks have become resistant to Frontline - However these pests have become resistant to some degree to all pesticides and no independent research exists to confirm this claim. I can assure you I've researched this in the greatest depth.
The bottom line is this - all of these products pose a risk.
The wise choice is to minimize that risk in your effort to protect your best friend from the diseases these vermin carry. Again, these diseases can be infinitely more lethal than the ingredients of the protection. To that end your safest and most effective choice is Frontline or Frontline Plus.
In the event your pet has a bad reaction to Frontline products these are the symptoms you would see:
* Restlessness
* Itching
* Vomiting
* Difficulty Breathing
* Lethargy
Should these symptoms occur, of course take your pet to your Veterinarian or emergency clinic immediately. It should be a comfort to know that unlike the toxic ingredients in most other flea and tick control products severe reactions to both Fipronil and Methoprene are rare.